ACTH anticorps (AA 1-24)

N° du produit ABIN5542231

Cet anticorps anti-ACTH est un anticorps Souris Monoclonal détectant ACTH dans IHC (p) et EIA. Adapté pour Humain et Rat.

Aperçu rapide pour ACTH anticorps (AA 1-24) (ABIN5542231)

Antigène: ACTH (Adrenocorticotropic hormone (ACTH))

Reactivité: Humain, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ACTH est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Clone: 57 (BGN-1388-66)

Détail du produit anti-ACTH anticorps

Épitope: AA 1-24

Séquence: SYSMEHFRWG KPVGKKRRPV KVYP

Specificité: This antibody recognizes 1-24 ACTH (Synacthen) which, as a synthetic analogue of naturally-occurring Adrenocorticotropic Hormone, can be used to measure adrenal reserve and for the diagnosis of adrenal insufficiency by acute adrenocortical stimulation. It does not recognize 17-39 ACTH (CLIP). Species: Human. Cross-reacts with Rat N-terminal ACTH.

Purification: Affinity Chromatography on Protein A

Immunogène: Synthetic peptide corresponding to the amino acids 1-24 of the Human ACTH conjugated to Keyhole Limpet Haemocyanin.

Isotype: IgG1

Information d'application

Indications d'application: ELISA. Immunohistochemistry on Formalin Fixed Paraffin Embedded Sections: 1/100-1/200 (Requires protein digestion pre-treatment of paraffin sections e.g. trypsin or pronase).

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.2 Preservatives: 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur ACTH

Antigène: ACTH (Adrenocorticotropic hormone (ACTH))

Classe de substances: Hormone

Sujet: ACTH, released from the anterior pituitary gland in response to corticotropin-releasing hormone from the hypothalamus, acts on the adrenal cortex to stimulate the production of corticosteroids such as cortisol, involved in the response to stress. Studies have shown that the administration of 1-24 ACTH increases blood pressure, believed to be attributed to an increase in ACTH-stimulated cortisol secretion, in association with increased cardiac output.

Pathways: Metabolism of Steroid Hormones and Vitamin D, Peptide Hormone Metabolism, Hormone Activity